What is the primary pharmaceutical packaging?
Pharmaceutical packaging is one of the most important areas of the pharmaceutical industry. The packaging is responsible for the protection of the drug during the sale, storage, and use. The packaging is done with the objective of containment, physical and chemical protection, portion control, and security of the drug.
Primary packaging means the material that is the first to come in direct contact with the drug which should be inert and chemically unreactive with the product. Primary pharmaceutical packaging is also called sales packaging.
Types of primary pharmaceutical packaging
1 – Ampoules
It is a small glass or plastic container and is used for packaging the liquid sample that must be protected from air and other contaminants. Ampoules are opened by snapping off the neck. Glass ampoules are generally more expensive than the other types of drug packaging. The abbreviation used for ampoules in parenteral packaging is the amp
2 – Blister packaging
In this type of packaging, a cavity is carved out in a thermoformed plastic and the drug in the form of a tablet or capsule is then kept in the cavity. After that, it is sealed on the open side with plastic or aluminum foil. 85% of the solid unit doses are packed in a blister in Europe. Blister packs are generally pre-formed plastic, paper, or foil.
3 – Bottles
Bottles are often used for packing liquid as well as solid drugs such as tablets and capsules. Glass is the first choice for liquids because it has excellent barrier properties. To pack tablets and capsules, especially for prescription bottles, plastic is used. The bottles come in different colors but orange to light brown are most common because these colors tend to block the ultraviolet rays from harming the potentially photosensitive contents.
4 – Sachet packaging
It is a square or rectangular sealed pouch made up of some type of plastic. They are often used to pack powder dosages but can also be used for liquids. They can be resealable or single-use sachets.
5 – Strip package
It is a unit dosage form of packaging. This type of packaging increases the shelf life of the dosage and also each content is protected individually.
6 – Vials
A glass or plastic container used to contain liquid, solid, or powder dosage form is called a vial. They are comparatively bigger than the ample in size and capacity. There are three types of closure options available for glass vials which are screw vials (closed with a screw cap or dropper), lip vials (closed with a plastic stopper or cork), and crimp vials (closed with a rubber stopper and a metal cap). The plastic vials can have other closure systems as well such as hinge caps which snap shut when pressed.
The type of packaging largely depends on the form and chemical composition of the drug. For instance, the most commonly used packaging for capsules and tablets is blister, strip, and alu-alu. For the liquid form of drugs, high-quality plastic or glass is used. Some materials that are used in primary packaging are as under. Read them to know about the packaging material options.
Glass is one of the most commonly used materials for primary packaging because the glass is chemically inert and inspection of the content in the container is easy. But the glass is very delicate and costly in comparison to the plastic.
The plastic used in the packaging is polyethylene, polyvinyl chloride, polypropylene, and polystyrene. Plastic is flexible, low weight, and cost-effective material. But plastic has a low level of inertness in comparison to glass and permeability to vapor and gas.
Steel, aluminum, and alloys of aluminum are the common metals used in the packaging. Metal is generally used for the packing of the dosage in gel forms. Metals have a risk of chemical reaction with the product. Therefore, tin or plated tin is often used because of its low reactivity as compared to other metals.
ZENES BIOTECH (Ayurvedic medicine manufacturers in Haryana)
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